One of the most important aspects of restorative dentistry is the material chosen for replacing and reproducing the natural tooth structure. As dentists, we require an adhesive which naturally adheres well to the tooth substance in addition to all the filling and restoration materials, e.g., composites, metals, ceramics and zirconium which may be used. With the new universal adhesive, Futurabond U (VOCO), an extremely strong bond to a variety of materials can be achieved. In order to highlight the wide range of applications of Futurabond U the author has described a variety of clinical cases in which this adhesive contributed to the success of the treatment.